A team scientists has determined the high-resolution atomic structure of a cell-surface receptor that most strains of HIV use to get into human immune cells.
Above: The new Science Express study reveals the structure of the CCR5 cell surface receptor, which most strains of HIV use to enter human immune cells. This image shows CCR5 side-by-side with alternate HIV co-receptor CXCR4. While the two share similar overall architecture, their binding pockets show important differences in shape and charge distribution. (Credit: Image courtesy of the Wu lab)
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